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The Pan Caribbean Partnership on HIV/AIDS (PANCAP) is established as HIV becomes the number one cause of death for 15-44 year-olds.

The new Global Fund to Fight AIDS, Tuberculosis and Malaria starts work, raising and investing money to defeat the three diseases.

Amid AIDS denialism, the Durban AIDS conference highlights the huge disparity in access to treatment between developed and developing countries.

“We need to look at the question that is posed, understandably I suppose: does HIV cause AIDS? AIDS the acronym stands for Acquired Immune Deficiency Syndrome. Now I do believe that is a sensible thing to ask: does one virus cause a syndrome? A virus cannot cause a syndrome. A virus will cause a disease.”
– Thabo Mbeki, President of South Africa, National Assembly, September 2000.

The World Trade Organization’s Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) is signed making the production of generics more difficult.

“I’m well. I’m healthy. This is my story.”
- Doris, Ghana

US basketball star Magic Johnson announces he is living with HIV.

Red ribbon is created as a symbol of HIV awareness.

Ryan White – the ‘child face of AIDS’ in the USA who provoked a worldwide movement of compassion for people living with HIV – dies aged 18.

The first World AIDS Day is held.